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Comparison between type A and type B early adiposity rebound in predicting overweight and obesity in children: a longitudinal study

Abstract : Early adiposity rebound (EAR) predicts paediatric overweight/obesity, but current approaches do not consider both the starting point of EAR and the BMI trajectory. We compared the clinical characteristics at birth, age 3-5 and 6-8 years of children, according to the EAR and to its type (type A/type B-EAR). We assessed the children's odds of being classified as overweight/obese at age 6-8 years, according to the type of EAR as defined at age 3-5 years. As part of this two-wave observational study, 1055 children were recruited and examined at age 3-5 years. Antenatal and postnatal information was collected through interviews with parents, and weight and height from the health records. Type A and type B-EAR were defined in wave 1 according to the BMI nadir and the variation of BMI z-score between the starting point of the adiposity rebound and the last point on the curve. At 6-8 years (wave 2), 867 children were followed up; 426 (40·4 %) children demonstrated EAR. Among them, 172 had type A-EAR, higher rates of parental obesity (P < 0·05) and greater birth weight compared with other children (P < 0·001). Odds for overweight/obesity at 6-8 years, when adjusting for antenatal and postnatal factors, was 21·35 (95 % CI 10·94, 41·66) in type A-EAR children and not significant in type B-EAR children (OR 1·76; 95 % CI 0·84, 3·68) compared with children without EAR. Classification of EAR into two subtypes provides physicians with a reliable approach to identify children at risk for overweight/obesity before the age of 5 years.
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https://hal.uca.fr/hal-03013145
Contributor : David Thivel <>
Submitted on : Wednesday, November 18, 2020 - 7:00:09 PM
Last modification on : Thursday, November 26, 2020 - 2:26:03 PM

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Johanna Roche, Sylvain Quinart, David Thivel, Stéphanie Pasteur, Frederic Mauny, et al.. Comparison between type A and type B early adiposity rebound in predicting overweight and obesity in children: a longitudinal study. British Journal of Nutrition, Cambridge University Press (CUP), 2020, 124 (5), pp.501-512. ⟨10.1017/S0007114520000987⟩. ⟨hal-03013145⟩

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