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Glioblastomas extension on DTI: prospective and comparative study versus metastases and healthy subjects

Youssef El Ouadih 1, 2 Céline Botella 2 Jerome Coste 1, 2 Bruno Pereira 3 Anna Sontheimer 2 Béatrice Claise 4 Jean-Jacques Lemaire 1, 2
1 IP - Institut Pascal - Clermont Auvergne
2 Service de Neurochirurgie [Clermont-Ferrand]
3 Unité de biostatistiques
4 Unité de neuroradiologie, service de radiologie
CHU Clermont-Ferrand
Abstract : Rationale Occult tumor cell invasion along white matter fibers is inapparent in conventional MRI. We aimed to precise glioblastomas extension on Diffusion Tensor Imaging (DTI) through a prospective and comparative study. Patients, material and methods Glioblastomas (n=15), metastases (n=9) and healthy controls (n=15) were included. DTI parameters were analyzed, particularly in the normal appearing white matter (NAWM) beyond peritumoral area. Results Specific DTI abnormalities were found in glioblastomas such as hyperanisotropia and morphological modifications in the NAWM.
Keywords : Metastasis behavior MRI mapping DTI Metastasis behaviour MRI Imaging Glioblastoma
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Conference papers
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https://hal.uca.fr/hal-02904258
Contributor : Youssef El Ouadih <>
Submitted on : Wednesday, July 22, 2020 - 9:22:04 AM
Last modification on : Thursday, July 23, 2020 - 11:36:48 AM

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  • HAL Id : hal-02904258, version 1

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PRES_CLERMONT | CNRS | INSTITUT_PASCAL | SIGMA-CLERMONT

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Youssef El Ouadih, Céline Botella, Jerome Coste, Bruno Pereira, Anna Sontheimer, et al.. Glioblastomas extension on DTI: prospective and comparative study versus metastases and healthy subjects. 3ème journée scientifique commune TGI-IP / MPS-ICCF / TechMed - CHU Clermont-Ferrand, CHU Clermont-Ferrand - TGI-IP / MPS-ICCF / TechMed, Sep 2019, Clermont-Ferrand, France. ⟨hal-02904258⟩

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