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Glioblastomas extension on DTI: prospective and comparative study versus metastases and healthy subjects

youssef El Ouadih 1, 2 Céline Botella 2 Jerome Coste 1, 2 Bruno Pereira 3 Anna Sontheimer 2 Béatrice Claise 4 Jean-Jacques Lemaire 1, 2 
1 IP - Institut Pascal
2 Service de Neurochirurgie [Clermont-Ferrand]
3 Unité de biostatistiques
4 Unité de neuroradiologie, service de radiologie
CHU Clermont-Ferrand
Abstract : Rationale Occult tumor cell invasion along white matter fibers is inapparent in conventional MRI. We aimed to precise glioblastomas extension on Diffusion Tensor Imaging (DTI) through a prospective and comparative study. Patients, material and methods Glioblastomas (n=15), metastases (n=9) and healthy controls (n=15) were included. DTI parameters were analyzed, particularly in the normal appearing white matter (NAWM) beyond peritumoral area. Results Specific DTI abnormalities were found in glioblastomas such as hyperanisotropia and morphological modifications in the NAWM.
Keywords : Glioblastoma MRI Imaging Metastasis behaviour DTI MRI mapping Metastasis behavior
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Conference papers
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https://hal.uca.fr/hal-02904258
Contributor : YOUSSEF EL OUADIH Connect in order to contact the contributor
Submitted on : Wednesday, July 22, 2020 - 9:22:04 AM
Last modification on : Sunday, June 26, 2022 - 2:52:02 AM

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  • HAL Id : hal-02904258, version 1

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PRES_CLERMONT | CNRS | INSTITUT_PASCAL

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youssef El Ouadih, Céline Botella, Jerome Coste, Bruno Pereira, Anna Sontheimer, et al.. Glioblastomas extension on DTI: prospective and comparative study versus metastases and healthy subjects. 3ème journée scientifique commune TGI-IP / MPS-ICCF / TechMed - CHU Clermont-Ferrand, CHU Clermont-Ferrand - TGI-IP / MPS-ICCF / TechMed, Sep 2019, Clermont-Ferrand, France. ⟨hal-02904258⟩

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