We present the results of a meso-scale systematic structural analysis of fractures, faults and dykes exposed at theSomma-Vesuvius volcano (southern Italy). Observed fractures include: (i) radial and tangential (with respect thecaldera axis), sub-metric to metric joints associated with the edifice load and volcano-tectonic activity (i.e.inflation, deflation and caldera collapse stages) and (ii) decameter-scale fractures related to volcanoflank in-stabilities. For the Somma-Vesuvius volcano, preexisting radial joints were commonly reactivated as transferfaults during the caldera formation, allowing different blocks to move toward the center of the collapsing area.Dykes occur with different geometries, includingen-echelonstructures bounding structural depressions. Theorientation analysis of all structures indicates that they are preferentially oriented. Furthermore, we provide amorphological lineament analysis using high-resolution Digital Terrain Models of Somma-Vesuvius. Azimuthand spatial distribution of dykes and morphological lineaments were analyzed for comparison with the oldSomma Crater and Gran Cono axes, respectively. Results highlight the overprinting of radial and clustered strainpatterns recorded in different volcano-tectonic evolution stages. We suggest a possible deformation evolutionmodel in which structures develop along either radial or preferential trends, highlighting different volcanicconditions: (i) where radial patterns occur, the structures developed during volcanic inflation cycles with aclosed magmatic conduit condition whereas (ii) clustered patterns are probably associated with a regional strainfield that overcomes the local deformationfield, a situation typical in the case of open-conduit activity