A multi-method investigation into Lauzière granite , located in the external Belledonne massif of the French Alps, reveals unusually hot hydrothermal conditions in vertical open fractures (Alpine-type clefts). The host-rock granite shows sub-vertical mylonitic microstructures and partial retrogression at temperatures of < 400 • C during Alpine tectonometamorphism. Novel zircon fission-track (ZFT) data in the granite give ages at 16.3 ± 1.9 and 14.3 ± 1.6 Ma, confirming that Alpine metamorphism was high enough to re-set the pre-Alpine cooling ages and that the Lauzière granite had already cooled below 240-280 • C and was exhumed to < 10 km at that time. Novel microthermometric data and chemical compositions of fluid inclusions obtained on milli-metric monazite and on quartz crystals from the same cleft indicate early precipitation of monazite from a hot fluid at T > 410 • C, followed by a main stage of quartz growth at 300-320 • C and 1.5-2.2 kbar. Previous Th-Pb dating of cleft monazite at 12.4 ± 0.1 Ma clearly indicates that this hot fluid infiltration took place significantly later than the peak of the Alpine metamorphism. Advective heating due to the hot fluid flow caused resetting of fission tracks in zircon in the cleft hanging wall, with a ZFT age at 10.3 ± 1.0 Ma. The results attest to the highly dynamic fluid pathways, allowing the circulation of deep mid-crustal fluids, 150-250 • C hotter than the host rock, which affect the thermal regime only at the wall rock of the Alpine-type cleft. Such advective heating may impact the ZFT data and represent a pitfall for exhuma-tion rate reconstructions in areas affected by hydrothermal fluid flow.