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Article Dans Une Revue Current Opinion in Plant Biology Année : 2014

Interplay between chromatin and RNA processing

Nicolas Bouche

Résumé

The processing of pre-mRNAs, including the selection of polyadenylation sites, is influenced by the surrounding chromatin context. We review here recent studies in Arabidopsis thaliana highlighting the intricate and reciprocal interplay between chromatin state and RNA processing. The studies have revealed that transcription can be influenced by the presence, in gene introns, of combination of epigenetic marks typical of heterochromatin. New factors binding to these marks have been identified and shown to play key roles in controlling the use of polyadenylation sites and processing of functional mRNAs. Concomitantly, several proteins of both the splicing and the polyadenylation machineries are also emerging as regulators of DNA methylation patterns and chromatin silencing.
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Dates et versions

hal-01204052 , version 1 (23-09-2015)

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Olivier Mathieu, Nicolas Bouche. Interplay between chromatin and RNA processing. Current Opinion in Plant Biology, 2014, 18, pp.60 - 65. ⟨10.1016/j.pbi.2014.02.006⟩. ⟨hal-01204052⟩
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