Conscious behaviors following bilateral pallido-thalamic low frequency stimulation in patients with continuing disorders of consciousness
Résumé
Deep brain stmulaton (DBS) has been proposed to enable consciousness recovery. We studied clinical effects of bilateral pallido-thalamic low frequency stmulaton intended to overdrive neuronal actvity. Five patents were included. Primary outcome was the analysis of scores of the Coma Recovery Scale Revised (CRS-R; 0-23). Statstcal analyses used random-effects models accountng between and within patent variability due to repeated measurements. We observed statstcally signifcant improvement of CRS-R during DBS-ON versus baseline (P1, P3) and CO-On versus baseline (P3). For the 5 patents auditory, visual, motor, oromotor-verbal, communicaton subscores of CRS-R were signifcantly improved.
Origine : Fichiers produits par l'(les) auteur(s)
Commentaire : Résumé non publié
Commentaire : Résumé non publié