In vivo evidence of the targeting of cartilaginous tissue by pyridinium functionalized nanoparticles - Université Clermont Auvergne Accéder directement au contenu
Article Dans Une Revue Chemical Communications Année : 2013

In vivo evidence of the targeting of cartilaginous tissue by pyridinium functionalized nanoparticles

Résumé

Ultrasmall gadolinium based particles have been functionalized with positively charged pyridinium quaternary ammonium and labelled with 111In. Evidence of their active targeting properties towards proteoglycans has been demonstrated in vivo after intravenous injection into rats opening thus a route to cancer imaging and therapy.
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Dates et versions

hal-00914993 , version 1 (06-12-2013)

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Jessica Morlieras, Jean-Michel Chezal, Elisabeth Miot-Noirault, Aurélien Vidal, Sophie Besse, et al.. In vivo evidence of the targeting of cartilaginous tissue by pyridinium functionalized nanoparticles. Chemical Communications, 2013, 49 (29), pp.3046-3048. ⟨10.1039/C3CC39106J⟩. ⟨hal-00914993⟩
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